@import url('https://fonts.googleapis.com/css2?family=Poppins:ital,wght@0,100;0,200;0,300;0,400;0,500;0,600;0,700;0,800;0,900;1,100;1,200;1,300;1,400;1,500;1,600;1,700;1,800;1,900&display=swap');

@import url('https://fonts.googleapis.com/css2?family=Inter:ital,opsz,wght@0,14..32,100..900;1,14..32,100..900&family=Poppins:ital,wght@0,100;0,200;0,300;0,400;0,500;0,600;0,700;0,800;0,900;1,100;1,200;1,300;1,400;1,500;1,600;1,700;1,800;1,900&display=swap');

body {
  margin: 0;
  padding: 0;
  box-sizing: border-box;
}
@media (max-width: 768px) {
  html,
  body {
    max-width: 100%;
    overflow-x: hidden;
  }
}

ul li a.nav-link {
  font-family: inter;
  font-weight: 600;
  font-size: 16px;
  color: #1c4f71;
}
h1,
h2,
h3,
h4,
h5,
h6 {
  font-family: railway;
}

body p {
  font-family: poppins;
  font-size: 16px;
}

.navbar {
  box-shadow: 0 2px 10px rgba(0, 0, 0, 0.05);
}
.btn {
  font-family: inter !important;
}
.btn:hover {
  background-color: #1c4f71 !important;
  border-color: #1c4f71 !important;
}
/* Hero Section */
.hero {
  background-color: #ffffff;
  padding: 10px 0px 50px 0px;
}

.hero-container {
  max-width: 1200px;
  margin: 0 auto;
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 40px;
}

/* Content */
.hero-content {
  flex: 1;
}

.hero-content h1 {
  font-size: 63px;
  font-weight: 700;
  color: #1c4f71; /* medical blue */
  margin-bottom: 20px;
  position: relative;
}

/* Accent underline */
.hero-content h1::after {
  content: "";
  display: block;
  width: 80px;
  height: 4px;
  background-color: #e65700; /* medical red */
  margin-top: 12px;
}

.hero-subtitle {
  font-size: 18px;
  line-height: 1.6;
  color: #444;
  /* max-width: 520px; */
  margin-bottom: 16px;
}

@media (max-width: 768px) {
  .hero-subtitle {
    text-align: center;
  }
}

.hero-ref {
  font-size: 13px;
  color: #777;
}

/* Visual */
.hero-visual {
  flex: 1;
  text-align: right;
}

.hero-visual img {
  max-width: 100%;
  height: auto;
}

/* Responsive */
@media (max-width: 768px) {
  .hero-container {
    flex-direction: column;
    text-align: center;
  }

  .hero-visual {
    text-align: center;
    margin-top: 30px;
  }

  .hero-content h1::after {
    margin-left: auto;
    margin-right: auto;
  }
  .hero-content h1 {
    font-size: 54px;
    line-height: 53px;
  }
}

/* Disease Overview Section */
.disease-overview {
  background-color: #f9fbfc;
  padding: 70px 20px;
  opacity: 1;
  transform: translateY(30px);
  transition: all 0.8s ease-out;
}

.disease-overview.show {
  opacity: 1;
  transform: translateY(0);
}

.overview-container {
  max-width: 1100px;
  margin: 0 auto;
  display: flex;
  align-items: center;
  gap: 40px;
}

/* Icon */
.overview-icon {
  flex: 0 0 120px;
  text-align: center;
}

.overview-icon img {
  width: auto;
  height: auto;
}
@media (max-width: 768px) {
  .overview-icon img {
    width: 345px;
    height: auto;
  }
}

/* Content */
.overview-content {
  flex: 1;
}

.overview-content h2 {
  font-size: 50px;
  color: #1c4f71;
  margin-bottom: 16px;
}

.overview-content p {
  font-size: 16px;
  line-height: 1.7;
  color: #444;
  max-width: 700px;
}

/* Responsive */
@media (max-width: 768px) {
  .overview-container {
    flex-direction: column;
    text-align: center;
  }

  .overview-icon {
    margin-bottom: 20px;
  }
}

/* GDMT Section */
.gdmt-section {
  background-color: #ffffff;
  padding: 80px 20px;
}

.gdmt-container {
  max-width: 1200px;
  margin: 0 auto;
  text-align: center;
}

/* Header */
.gdmt-header h2 {
  font-size: 34px;
  color: #1c4f71;
  margin-bottom: 16px;
}

.gdmt-highlight {
  font-size: 18px;
  color: #444;
  max-width: 760px;
  margin: 0 auto 50px;
  line-height: 1.6;
}

/* Cards */
.gdmt-cards {
  display: grid;
  grid-template-columns: repeat(4, 1fr);
  gap: 30px;
  margin-bottom: 40px;
}

.gdmt-card {
  background: #f9fbfc;
  padding: 30px 20px;
  border-radius: 8px;
  transition:
    transform 0.3s ease,
    box-shadow 0.3s ease;
}

.gdmt-card img {
  width: 60px;
  margin-bottom: 20px;
}

.gdmt-card h3 {
  font-size: 19px;
  font-weight: 500;
  color: #1c4f71;
  line-height: 1.4;
}

/* Hover effect (only elevation) */
.gdmt-card:hover {
  transform: translateY(-6px);
  box-shadow: 0 8px 20px rgba(0, 0, 0, 0.08);
}

/* Footer note */
.gdmt-note {
  font-size: 14px;
  color: #666;
  max-width: 800px;
  margin: 0 auto;
}

/* Responsive */
@media (max-width: 992px) {
  .gdmt-cards {
    grid-template-columns: repeat(2, 1fr);
  }
}

@media (max-width: 576px) {
  .gdmt-cards {
    grid-template-columns: 1fr;
  }
}

/* Sequencing Section */
.gdmt-sequencing {
  background-color: #f9fbfc;
  padding: 80px 20px;
}

.sequencing-container {
  max-width: 1200px;
  margin: 0 auto;
}

/* Header */
.sequencing-header {
  text-align: center;
  margin-bottom: 60px;
}

.sequencing-header h2 {
  margin-bottom: 16px;
  font-size: 34px;
  /* width: 912px; */
  text-align: center;
  margin: auto;
  padding-bottom: 20px;
  color: #1c4f71;
}

.sequencing-intro {
  font-size: 18px;
  color: #444;
  max-width: 760px;
  margin: 0 auto;
  line-height: 1.6;
}

/* Columns */
.sequencing-columns {
  display: grid;
  grid-template-columns: repeat(2, 1fr);
  gap: 40px;
  margin-bottom: 40px;
}

/* Sequence Blocks */
.sequence-block {
  background: #ffffff;
  padding: 30px;
  border-radius: 8px;
  border: 1px solid #e3e8ec;
}

.sequence-block.highlight {
  background-color: #1c4f71;
  padding: 30px;
  border-radius: 8px;
  border: 1px solid #1c4f71;
}

.sequence-block h3 {
  font-size: 23px;
  color: #1c4f71;
  margin-bottom: 20px;
}

/* Steps */
.sequence-steps {
  list-style: none;
  padding: 0;
  margin: 0 0 20px;
}

.sequence-steps-highlited {
  list-style: none;
  padding: 0;
  margin: 0 0 20px;
}

.sequence-steps .step {
  font-family: poppins;
  position: relative;
  padding: 12px 0 12px 28px;
  font-size: 15px;
  color: #333;
  opacity: 1;
  transition: opacity 0.4s ease;
}

.sequence-steps .step::before {
  content: "";
  position: absolute;
  left: 0;
  top: 18px;
  width: 10px;
  height: 10px;
  background-color: #1c4f71;
  border-radius: 50%;
}

.sequence-steps .stephighlited {
  font-family: poppins;
  position: relative;
  padding: 12px 0 12px 28px;
  font-size: 15px;
  color: #fffefe;
  opacity: 1;
  transition: opacity 0.4s ease;
}

.sequence-steps .stephighlited::before {
  content: "";
  position: absolute;
  left: 0;
  top: 18px;
  width: 10px;
  height: 10px;
  background-color: #ffffff;
  border-radius: 50%;
}

/* Active step */
.sequence-steps .step.active {
  opacity: 1;
  font-weight: 600;
}

/* Notes */
.sequence-note {
  font-size: 14px;
  color: #343434;
}
.sequence-note-highlited {
  font-size: 14px;
  color: #ffffff;
}

/* Footer note */
.sequencing-footer {
  text-align: center;
  font-size: 14px;
  color: #555;
  max-width: 813px;
  margin: 0 auto;
}

/* Responsive */
@media (max-width: 768px) {
  .sequencing-columns {
    grid-template-columns: 1fr;
  }
}

/* Key Therapies Section */
.key-therapies {
  background-color: #ffffff;
  padding: 80px 20px;
}

.therapies-container {
  max-width: 1200px;
  margin: 0 auto;
}

/* Header */
.therapies-header {
  text-align: center;
  margin-bottom: 60px;
}

.therapies-header h2 {
  font-size: 34px;
  color: #1c4f71;
}

/* Therapy Block */
.therapy-block {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 40px;
  margin-bottom: 80px;
}

.therapy-block.reverse {
  flex-direction: row-reverse;
}

/* Content */
.therapy-content {
  flex: 1;
}

.therapy-content h3 {
  font-size: 24px;
  color: #1c4f71;
  margin-bottom: 14px;
}

.therapy-content p {
  font-size: 16px;
  line-height: 1.7;
  color: #444;
  max-width: 520px;
}

/* Visual */
.therapy-visual {
  flex: 1;
  text-align: center;
  overflow: hidden;
}

.therapy-visual img {
  max-width: 100%;
  height: auto;
  transform: scale(0.95);
  transition: transform 0.8s ease;
}

/* Mild zoom on reveal */
.therapy-visual.show img {
  transform: scale(1);
}

/* Responsive */
@media (max-width: 768px) {
  .therapy-block,
  .therapy-block.reverse {
    flex-direction: column;
    text-align: center;
  }

  .therapy-content p {
    margin-left: auto;
    margin-right: auto;
  }
}

/* Clinical Evidence Section */
.clinical-evidence {
  background-color: #f9fbfc;
  padding: 80px 20px;
}

.evidence-container {
  max-width: 1200px;
  margin: 0 auto;
}

/* Header */
.evidence-header {
  text-align: center;
  margin-bottom: 60px;
}

.evidence-header h2 {
  font-size: 34px;
  color: #1c4f71;
}

/* Cards */
.evidence-cards {
  display: grid;
  grid-template-columns: repeat(2, 1fr);
  gap: 40px;
  margin-bottom: 40px;
}

.evidence-card {
  background: #ffffff;
  border-radius: 8px;
  padding: 40px 30px;
  border: 1px solid #e3e8ec;
  text-align: center;
}

.evidence-card h3 {
  font-size: 20px;
  color: #1c4f71;
  margin-bottom: 30px;
}

/* Metric */
.evidence-metric {
  font-size: 56px;
  font-weight: 700;
  color: #e65700;
  margin-bottom: 20px;
}

.evidence-metric .percent {
  font-size: 36px;
  margin-left: 4px;
}

/* Text */
.evidence-text {
  font-size: 15px;
  line-height: 1.6;
  color: #444;
  max-width: 420px;
  margin: 0 auto;
}

/* Footer note */
.evidence-note {
  text-align: center;
  font-size: 14px;
  color: #666;
  max-width: 800px;
  margin: 0 auto;
}

/* Responsive */
@media (max-width: 768px) {
  .evidence-cards {
    grid-template-columns: 1fr;
  }
}

/* Section background */
.beyond-benefits {
  background: #f8fafc;
  padding: 80px 20px;
}

/* Container */
.benefits-container {
  max-width: 1200px;
  margin: 30px auto;
  text-align: center;
}

/* Heading */
.benefits-header h2 {
  font-size: 32px;
  color: #0b3c5d;
  margin-bottom: 50px;
  font-weight: 500;
}

.benefits-header {
  margin-bottom: 70px;
}

/* Grid layout */
.benefits-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
  gap: 30px;
}

/* Card styles */
.benefit-card {
  background: #ffffff;
  padding: 40px 25px;
  border-radius: 12px;
  border: 1px solid #e5edf3;
  box-shadow: 0 8px 25px rgba(0, 0, 0, 0.06);
  transition: all 0.35s ease;
  cursor: pointer;
}

/* Hover animation */
.benefit-card:hover {
  transform: translateY(-10px);
  box-shadow: 0 18px 40px rgba(0, 0, 0, 0.12);
}

/* Icon */
.benefit-card img {
  width: 60px;
  margin-bottom: 20px;
  transition: transform 0.35s ease;
}

/* Icon hover effect */
.benefit-card:hover img {
  transform: scale(1.15);
}

/* Text */
.benefit-card p {
  font-size: 16px;
  color: #333;
  line-height: 1.5;
  margin: 0;
}

/* Responsive */
@media (max-width: 992px) {
  .benefits-grid {
    grid-template-columns: repeat(2, 1fr);
  }
}

@media (max-width: 576px) {
  .benefits-grid {
    grid-template-columns: 1fr;
  }
}

/* Dosage & Indications */
.dosage-indications {
  background-color: #f4f6f8;
  padding: 80px 20px;
}

.dosage-container {
  max-width: 1100px;
  margin: 0 auto;
}

.dosage-indications h2 {
  font-size: 34px;
  color: #1c4f71;
  margin-bottom: 40px;
  text-align: center;
}

/* Blocks */
.dosage-block {
  background-color: #ffffff;
  border: 1px solid #dfe5ea;
  border-radius: 6px;
  padding: 30px;
  margin-bottom: 30px;
}

.dosage-block h3 {
  font-size: 20px;
  color: #1c4f71;
  margin-bottom: 16px;
}

.dosage-block p {
  font-size: 15px;
  line-height: 1.7;
  color: #333;
  margin-bottom: 12px;
}

.dosage-block ul {
  padding-left: 20px;
}

.dosage-block li {
  font-size: 15px;
  font-family: poppins;
  line-height: 1.7;
  color: #333;
  margin-bottom: 10px;
}

/* Section background */
.dosage-indications {
  background-color: #f7f9fc;
  padding: 60px 0;
}

/* Container width */
.dosage-container {
  max-width: 900px;
  margin: 0 auto;
  padding: 0 20px;
}

/* Individual boxes */
.dosage-block {
  background: #ffffff;
  border-radius: 10px;
  padding: 25px 30px;
  margin-bottom: 30px;

  /* Default shadow */
  box-shadow: 0 8px 25px rgba(0, 0, 0, 0.08);

  /* Smooth animation */
  transition: all 0.35s ease;
}

/* Hover effect */
.dosage-block:hover {
  transform: translateY(-8px);
  box-shadow: 0 15px 35px rgba(0, 0, 0, 0.15);
}

/* Headings inside box */
.dosage-block h3 {
  font-size: 20px;
  color: #1c4f71;
  margin-bottom: 15px;
}

/* Paragraph text */
.dosage-block p {
  color: #444;
  line-height: 1.7;
  margin-bottom: 10px;
}

/* Bullet list */
.dosage-block ul {
  padding-left: 20px;
}

.dosage-block ul li {
  margin-bottom: 10px;
  line-height: 1.6;
  color: #333;
}

/* Optional: subtle left border accent */
.dosage-block {
  /* border-left: 4px solid #e65700; */
  border-left: 4px solid #1c4f71;
}

/* ================================
   SAFETY / PRESCRIBING INFO SECTION
================================ */

.safety-info {
  background: #eef1f4;
  padding: 80px 20px;
}

.safety-container {
  max-width: 1000px;
  margin: 0 auto;
}

.safety-container h2 {
  text-align: center;
  font-size: 32px;
  color: #1c4f71;
  margin-bottom: 30px;
  font-weight: 600;
}

/* ================================
   SCROLL CONTAINER
================================ */

.safety-scroll {
  background: #ffffff;
  max-height: 380px;
  overflow-y: auto;
  padding: 30px;
  border-radius: 12px;
  box-shadow: 0 10px 30px rgba(0, 0, 0, 0.08);
  scroll-behavior: smooth;
}

/* Custom scrollbar (Chrome / Edge) */
.safety-scroll::-webkit-scrollbar {
  width: 8px;
}

.safety-scroll::-webkit-scrollbar-thumb {
  background: #1c4f71;
  border-radius: 10px;
}

.safety-scroll::-webkit-scrollbar-track {
  background: #e6ebef;
}

/* ================================
   SAFETY BLOCKS
================================ */

.safety-block {
  background: #f9fbfc;
  padding: 22px 24px;
  border-radius: 10px;
  margin-bottom: 25px;
  border-left: 5px solid #1c4f71;
  box-shadow: 0 6px 18px rgba(0, 0, 0, 0.06);
  transition: all 0.35s ease;
  animation: fadeUp 0.6s ease both;
}

/* Hover animation */
.safety-block:hover {
  transform: translateY(-6px);
  box-shadow: 0 14px 35px rgba(28, 79, 113, 0.25);
  border-left-color: #e65700;
}

/* ================================
   HEADINGS & TEXT
================================ */

.safety-block h3 {
  color: #1c4f71;
  font-size: 20px;
  margin-bottom: 12px;
  font-weight: 600;
}

.safety-block ul {
  padding-left: 18px;
}

.safety-block li {
  font-size: 15px;
  color: #444;
  line-height: 1.7;
  margin-bottom: 8px;
}

/* ================================
   FADE-UP ANIMATION
================================ */

@keyframes fadeUp {
  from {
    opacity: 0;
    transform: translateY(20px);
  }
  to {
    opacity: 1;
    transform: translateY(0);
  }
}

/* Final Soft CTA */
.final-cta {
  background-color: #ffffff;
  padding: 60px 20px 80px;
  border-top: 1px solid #e1e6eb;
  background-image: url(../images/familiy.jpg);
  min-height: 900px;
  background-size: cover;
  background-repeat: no-repeat;
  opacity: 0.9;
}

.cta-container {
  max-width: 1100px;
  margin: 0 auto;
  text-align: center;
}

/* Main statement */
.cta-text {
  font-size: 20px;
  line-height: 1.6;
  color: #1c4f71;
  max-width: 800px;
  margin: 0 auto 16px;
  font-weight: 500;
}

/* Reference line */
.cta-reference {
  font-size: 13px;
  color: #666;
}

/* Tablet & mobile */
@media (max-width: 768px) {
  .cta-text {
    font-size: 18px;
  }
}